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Type 2 Diabetes -Comparing newer premixed insulin and pills for diabetes

Comparing Medicines

Research studies have compared newer premixed insulin with other diabetes medicines. This research can help you and your doctor decide whether newer premixed insulin might be a good choice for you. In these charts, a checkmark means research shows the medicine works better than the medicine it is compared with.

Comparing newer premixed insulin and pills for diabetes

Newer premixed insulin can lower blood sugar more than pills for diabetes. Newer premixed insulin is more likely to cause very low blood sugar. It can also cause more weight gain than diabetes pills.

Pills for diabetes Newer premixed insulin
Benefits
Better at lowering A1c.
checkmark
Better at lowering fasting blood sugar (before eating).
checkmark
Better at lowering blood sugar after meals.
checkmark
Side Effects
Less hypoglycemia (very low blood sugar).
checkmark
Less weight gain.
checkmark

Comparing newer premixed insulin and long-acting insulin

Newer premixed insulin can lower A1c and blood sugar after meals more than long-acting insulin. But long-acting insulin is better at lowering blood sugar before eating. Newer premixed insulin is more likely to cause very low blood sugar. It can also cause more weight gain than long-acting insulin.

Long-acting insulin Newer premixed insulin
Benefits
Better at lowering A1c.
checkmark
Better at lowering fasting blood sugar (before eating).
checkmark
Better at lowering blood sugar after meals.
checkmark
Side Effects
Less hypoglycemia (very low blood sugar).
checkmark
Less weight gain.
checkmark

Comparing newer premixed insulin and premixed NPH/regular insulin

The different types of premixed insulin work about the same. Newer premixed insulin is better at lowering blood sugar after meals.

Premixed
NPH/regular insulin
Newer
premixed insulin
Benefits
Better at lowering A1c.
Work the same.
Better at lowering fasting blood sugar (before eating).
Work the same.
Better at lowering blood sugar after meals.
checkmark
Side Effects
Less hypoglycemia (very low blood sugar).
Work the same.
Less weight gain.
Work the same.